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Persistent Cough
When It Has Gone on Long Enough to Need Looking At

Most persistent coughs have a common, manageable cause — a virus that has left airway irritation behind, gastric reflux, or post-nasal drip. But a cough that has lasted more than three weeks without a clear explanation is worth investigating properly. Some thoracic causes — including early lung cancer — are best found early, when the most treatment options are available. Dr Lawrence Okiror, Consultant Thoracic and Robotic Surgeon (GMC 6150382), sees patients at London Bridge Hospital within 2–3 days. If the cause turns out not to be surgical, he will tell you so and refer you to the right colleague. The goal is a clear answer, not a surgical one.

Last reviewed: April 2026 · Dr Lawrence Okiror FRCS(CTh) FRCSEd(CTh) · GMC 6150382

Three Weeks Is the Threshold

A cough that has lasted more than three weeks without a clear explanation — no recent infection, no obvious cause — is worth a specialist review. In a smoker or ex-smoker, the threshold is lower. A chest X-ray is not sensitive enough to rule out all thoracic causes — a CT scan is more reliable.

Non-Smokers Are Not Exempt

Lung cancer in people who have never smoked is a recognised and growing clinical picture. These cancers respond well to targeted treatments when found early. A persistent cough in a never-smoker without an obvious explanation is worth investigating rather than dismissing.

The Right Answer, Not a Surgical One

Many persistent coughs have non-surgical causes. If investigation shows something better managed by a respiratory physician or medical oncologist, Dr Okiror will tell you so and refer you directly to the right colleague at the same institutions. You get a clear answer either way.

What are the most common causes of a persistent cough?

Most persistent coughs have a common, treatable cause — the aftermath of a chest infection, gastric reflux irritating the airway, asthma, or mucus dripping from the back of the nose. These are all manageable. The less common but important causes are chest-specific: a lung nodule, fluid around the lung, a problem in the central airways, or — less commonly — lung cancer.

I have never smoked. Can I still have a lung problem?

Yes. Lung cancer in people who have never smoked is increasingly recognised as a distinct condition, often driven by specific genetic changes that respond well to modern targeted treatments. GSTT, where Dr Okiror operates, has an active research programme on this. Never-smoking history does not rule out a thoracic cause — it just changes what that cause is likely to be.

What if the cause isn't surgical?

If investigation reveals a cause that is better managed by a respiratory physician or medical oncologist — such as asthma, reflux, or a medical lung condition — Dr Okiror will tell you so directly. He will refer you to a trusted colleague at GSTT or London Bridge Hospital who shares his commitment to patient-centred, unhurried care. The referral is direct and personal, not a generic letter.

Do I need a GP referral?

No. You can contact the practice directly and be seen within 2–3 days at London Bridge Hospital. If you have already had a chest X-ray or CT scan done, bring the images. Dr Okiror reviews them personally at the first appointment and can give an informed assessment without any duplication of tests. New consultations from £250.

The Chest-Specific Causes
Worth Ruling Out

Once common causes have been excluded — no reflux, no post-nasal drip, not on an ACE inhibitor medication — the following thoracic causes are the ones a specialist looks for. All are identifiable on CT scan and all are treatable.

Lung Nodule or Early Lung Cancer

A nodule or tumour in the lung or central airways can cause a cough. This is the most important cause to rule out — not because it is the most common, but because finding it early, when it is still small, makes a significant difference to the treatment options available. CT scan is the right investigation — a chest X-ray can miss it entirely.

Lung nodule & cancer →

Central Airways Problem

A narrowing, growth, or inflammation in the trachea or main bronchi (the large central airways) causes a distinctive persistent cough — often dry with a slightly barking quality. A bronchoscopy (a small camera in the airway) diagnoses this and can often treat it at the same procedure. Dr Okiror leads the Central Airways Service at GSTT.

Central airways →

Fluid Around the Lung

A build-up of fluid between the lung and the chest wall (pleural effusion) causes irritation and a persistent cough, usually alongside breathlessness. The fluid can be drained, the underlying cause identified from the fluid analysis, and the appropriate treatment started. This is a straightforward procedure. Pleural disease →

Emphysema or COPD

Chronic airway inflammation from emphysema or COPD causes a persistent productive cough, often with breathlessness on exertion. For patients whose symptoms are not controlled by inhalers, there are further specialist options including endobronchial valve therapy and lung volume reduction surgery. Emphysema treatment →

The Goal Is the Right Answer
Not a Surgical One

“If investigation finds a cause that is not surgical — a medical lung condition, gastric reflux causing a chronic cough, or a pattern better managed by a respiratory physician or medical oncologist — I will tell you so directly at the consultation. Where appropriate, I refer to specialist colleagues at GSTT and London Bridge Hospital who share my commitment to patient-centred care and honest, unhurried discussion of options. These are colleagues I work with closely at both institutions. The referral is direct and personal.”

— Dr Lawrence Okiror, Consultant Thoracic and Robotic Surgeon

Questions About
Persistent Cough

Questions most commonly asked by patients with a cough that has lasted more than three weeks.

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Or call Jo Mitchelson:
020 7952 2882

When should a persistent cough be investigated?
Three weeks without a clear explanation. If there has been no recent chest infection, no hay fever, no post-nasal drip, and you are not on a blood pressure medication called an ACE inhibitor, a cough lasting beyond three weeks warrants a specialist opinion. In a smoker or ex-smoker, the threshold is lower. If there is any weight loss, breathlessness, fatigue, or blood in the sputum alongside the cough, assessment should be prompt.
What are the common causes?
Most persistent coughs have a manageable cause: the lingering irritation after a chest infection, gastric reflux, asthma, or mucus from the back of the nose. These are not serious. The less common but important chest-specific causes include a lung nodule, fluid around the lung, a central airways problem, or lung cancer. Investigation identifies clearly which applies.
Can someone who has never smoked have a lung problem causing a cough?
Yes. Lung cancer in people who have never smoked is a recognised and growing picture. These cancers tend to be driven by specific genetic changes — including EGFR, ALK, and ROS1 mutations — that respond well to targeted treatments when found early. GSTT, where Dr Okiror performs NHS surgery, has an active research programme on this. Never-smoking history does not rule out a thoracic cause for a cough.
What if the cause turns out not to need surgery?
Many causes of persistent cough are not surgical. If Dr Okiror finds a cause better managed by a respiratory physician or medical oncologist, he will tell you so directly and refer you to the right colleague at GSTT or London Bridge Hospital — colleagues he works with regularly at both institutions. The referral is direct, personal, and within the same institutional network. The goal is the right answer for you, not a surgical one.
What investigation is needed?
A CT chest scan is more reliable than a chest X-ray and is the right investigation when a cough has lasted beyond three weeks without explanation. A normal chest X-ray does not rule out early lung cancer or other thoracic causes. Where CT shows a nodule, the next steps — monitoring, biopsy, or surgery — are determined by the specific appearance and risk scoring of what is found. Dr Okiror coordinates the full assessment from the first appointment.
Do I need a GP referral?
No. You can contact the practice directly and be seen within 2–3 days at London Bridge Hospital. If you have had a chest X-ray or CT scan already, bring the images — Dr Okiror reviews them personally at the first appointment. New consultations from £250. Most major insurers accepted. Second opinions also available.

A cough lasting months
deserves a clear answer.

No GP referral required. Private appointments at London Bridge Hospital within 2–3 days. Dr Okiror will review your imaging personally and tell you clearly what the investigation shows — and what, if anything, needs to happen next.

Book an Assessment → Second Opinion

Jo Mitchelson, Private PA  ·  020 7952 2882  ·  pa@lungsurgeon.co.uk

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