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Combined Lung Biopsy
and Robotic Surgery

For carefully selected fit patients with a small peripheral lung lesion, it is possible to perform biopsy and curative robotic surgery under a single anaesthetic. If the in-theatre preliminary assessment signals lung cancer, surgical resection proceeds immediately. If it does not, the patient wakes with no incisions and goes home the same day. All five technologies required for this pathway are available at London Bridge Hospital.

Last reviewed: April 2026 · Dr Lawrence Okiror FRCS(CTh) FRCSEd(CTh) · GMC 6150382

Diagnosis First.
Surgery Only if Justified.

For most patients with a suspicious lung lesion, the pathway from biopsy to surgical treatment spans several weeks: bronchoscopy or CT biopsy, laboratory pathology, MDT discussion, surgical listing, pre-operative assessment, separate admission for resection.

For a carefully selected group of fit patients with small peripheral tumours, that journey can be condensed into a single anaesthetic episode. Biopsy, preliminary in-theatre diagnosis, dye marking and robotic segmentectomy — one procedure, one admission, one recovery.

The defining principle of this approach is that surgical commitment follows the preliminary diagnosis — it does not precede it. If the in-theatre preliminary assessment does not signal cancer, the procedure ends. No incisions are made. The patient wakes and goes home the same day.

What this pathway offers
  • Diagnosis before surgical commitment Surgery only proceeds if the preliminary in-theatre assessment justifies it. If not, the patient has no incisions.
  • One anaesthetic for both steps Bronchoscopic biopsy and robotic resection under a single general anaesthetic for qualifying patients.
  • Same-day discharge Whether or not resection proceeds, patients go home the same day with a preliminary result.
  • Treatment within days of referral For privately insured or self-pay patients who qualify, the full pathway from referral to completed surgery is measured in days, not months.

This pathway is offered to a select group of patients. Suitability is assessed individually at consultation. It is not appropriate for all patients with lung lesions.

Different From
Frozen Section Analysis

Intraoperative frozen section analysis and proceed to resection has been performed for decades. This pathway is fundamentally different. The distinction matters clinically and for patients choosing between approaches.

Conventional Approach

Frozen Section Analysis

The patient undergoes open or keyhole surgery first. The nodule is removed and sent for rapid frozen section pathology while the patient remains on the operating table.

If the result confirms cancer, anatomical resection proceeds. If it does not, the patient has still had a surgical incision, still had a wedge resection performed, and still faces a recovery.

Surgical commitment precedes diagnosis.

This Pathway

ION with ROSE, then Proceed

ION bronchoscopy reaches the lesion through the airways — no incision required. An onsite cytopathologist provides a preliminary assessment of the biopsy in theatre.

If the preliminary assessment signals lung cancer, dye marking and robotic resection follow immediately. If it does not, the patient has had no surgical incisions. They wake and go home the same day.

Surgical commitment follows diagnosis.

The key distinction: In the frozen section pathway, a surgical operation has already been performed before any tissue result is available. In this pathway, the patient undergoes no surgical incision unless the preliminary in-theatre assessment provides justification. For patients whose lesion turns out to be benign or non-malignant, this is the difference between an operation and a bronchoscopy.

Five Technologies.
One Theatre Session.

Under a single general anaesthetic, five specialist technologies are combined in sequence. Each step depends on the one before it. The decision to proceed to surgery is made in theatre, informed by the ROSE preliminary assessment, pre-operative imaging, and clinical judgement.

1
ION Navigational Bronchoscopy

The ION robotic bronchoscopy platform navigates to the peripheral lung lesion through the airways. No incision is made at this stage. ION can reach lesions in the outer third of the lung that conventional bronchoscopes cannot access — the population of nodules where biopsy has historically been most difficult.

2
Cone Beam CT

Real-time intraoperative imaging confirms the position of the probe at the lesion before the biopsy is taken. This step reduces the risk of sampling error — a critical safeguard when proceeding to immediate surgery depends on the result being reliable. Cone beam CT is used on every case in this pathway, not selectively.

3
Onsite ROSE — Rapid On-Site Evaluation

A cytopathologist is present in the operating theatre. The biopsy sample is assessed immediately, providing a preliminary signal within minutes. ROSE is not a definitive histological diagnosis — formal pathology follows in the laboratory in the usual way. If the preliminary assessment does not signal cancer, the procedure ends here. No surgical incisions are made. The patient wakes and goes home the same day.

4
Dye Marking

If ROSE provides a preliminary signal of non-small cell lung cancer and the decision is made to proceed, the lesion is marked with dye. This intraoperative localisation guides the subsequent robotic resection, ensuring precise identification of the target lung segment on the outer surface of the lung.

5
Robotic Segmentectomy

The da Vinci Xi robotic platform is used to perform an anatomical segmentectomy — removal of the specific lung segment containing the tumour — through small keyhole incisions. Anatomical segmentectomy preserves more healthy lung tissue than wedge resection and delivers appropriate oncological resection margins for early-stage non-small cell lung cancer. Robotic segmentectomy overview →

Who This
Pathway Is For

This is not a routine pathway and is not appropriate for most patients with a lung lesion. It is considered for a specific group where the clinical picture supports combining biopsy and resection in a single anaesthetic episode.

The workup required before the procedure is straightforward — CT chest, PET-CT, lung function tests and routine blood tests. Patients who need invasive staging, complex mediastinal assessment, or who have significant comorbidities are generally not suitable.

Suitability is assessed at an individual consultation. If on review the clinical picture does not support the combined approach, a staged pathway is planned. No patient is committed to this sequence before the full assessment is complete.

Typical criteria for consideration
  • Fit patient with no significant comorbidities precluding extended general anaesthesia
  • Small peripheral lung tumour accessible to navigational bronchoscopy
  • Imaging characteristics consistent with a resectable lesion
  • No requirement for complex invasive staging such as EBUS or mediastinoscopy
  • Standard pre-operative workup sufficient: CT, PET-CT, lung function, bloods

This pathway is most appropriate for privately insured or self-pay patients who wish to move from diagnosis to treatment at pace and who meet the clinical criteria above. It is not suitable for everyone. In some cases, combining diagnostic bronchoscopy and surgical treatment in a single procedure may be appropriate. Coverage for this approach varies between insurers, and where needed, options can be discussed with Jo Mitchelson in advance of any commitment.

Where the Procedure
Takes Place

Dr Okiror consults and operates at both London Bridge Hospital and The Lister Hospital Chelsea. For this specific combined pathway, London Bridge Hospital is the appropriate venue for private patients. It holds all five required technologies — ION bronchoscopy, cone beam CT, onsite ROSE, dye marking capability and the da Vinci Xi robotic platform — and has the infrastructure to coordinate them within a single theatre session.

London Bridge Hospital

Primary private facility for this pathway. All five technologies in place. Ranked among the top ten hospitals in the UK — Newsweek World's Best Hospitals 2026.

The Lister Hospital, Chelsea

Dr Okiror's second private operating base. Suitable for many lung surgery cases. Consultations and follow-up can take place at whichever hospital is more convenient.

This combined same-anaesthetic pathway has been developed and performed as part of Dr Okiror's practice. All five technologies required for this approach are in place at London Bridge Hospital for private patients assessed as suitable. Each case is evaluated individually at consultation. This pathway is offered to a carefully selected group of patients and is not appropriate for everyone.

The Surgical Record
Behind the Pathway

The viability of this combined pathway depends on robotic surgical expertise at volume. The operative data below reflects Dr Okiror's personal record.

507

Personal da Vinci robotic cases to April 2026

85 min

Average robotic lobectomy — vs 129 min European average

95

Robotic segmentectomies performed

99.16%

Operative survival rate — vs 98.5% national average

Robotic operative times from Intuitive Surgical platform data. Survival and resection figures from SCTS National Thoracic Audit 2024–25. European average from Intuitive Surgical European benchmarking data.

Questions About
This Pathway

Questions from patients and referring physicians about the combined biopsy and robotic surgery pathway.

Book a Consultation →

Or call Jo Mitchelson:
020 7952 2882

What is the combined biopsy and robotic surgery pathway?
It is a single-anaesthetic procedure combining ION navigational bronchoscopy, cone beam CT, onsite ROSE cytopathology, dye marking and robotic segmentectomy. If the in-theatre preliminary assessment signals non-small cell lung cancer, surgical resection proceeds immediately. If it does not, the patient wakes with no incisions and goes home the same day.
How is this different from intraoperative frozen section analysis?
With frozen section analysis, the patient has already had an operation before any tissue result is known — surgical commitment comes first. In this pathway, the preliminary biopsy result comes first. Surgery only proceeds if the in-theatre assessment justifies it. If it does not, the patient has had no surgical incisions.
Who is suitable for this pathway?
Fit patients with small peripheral lung tumours that do not require complex invasive staging. Standard workup — CT, PET-CT, lung function tests and routine blood tests — is sufficient. Suitability is assessed individually at consultation. This pathway is not appropriate for all patients.
What happens if the biopsy does not confirm cancer?
If the onsite preliminary assessment does not signal cancer, no surgical incisions are made. The patient wakes from the anaesthetic, recovers, and goes home the same day. A preliminary result is available immediately. Final pathology from the bronchoscopy sample follows through the laboratory in the normal way.
Is ROSE a definitive diagnosis?
No. ROSE — Rapid On-Site Evaluation — provides a preliminary in-theatre cytopathological assessment only. It is not a substitute for formal histological diagnosis, which follows from laboratory analysis of the tissue sample. The decision to proceed to surgery is based on the ROSE preliminary signal in combination with all pre-operative imaging and clinical assessment.
Where is this procedure available privately?
All five technologies required — ION bronchoscopy, cone beam CT, onsite ROSE, dye marking and the da Vinci Xi robotic platform — are available at London Bridge Hospital. Suitability for this pathway is assessed at consultation.
Will my private medical insurance cover this pathway?
It depends on your policy. When two procedures are performed under the same anaesthetic, most private medical insurers apply a multiple procedure discount — typically reimbursing the primary procedure (robotic segmentectomy) in full and the bronchoscopy element at a reduced rate. Some policies may treat elements of the pathway differently. Jo Mitchelson contacts your insurer before any procedure to obtain pre-authorisation and establishes exactly what will and will not be covered, so there are no unexpected costs. For self-pay patients, a transparent all-in quote is available on request. Contact Jo on 020 7952 2882 or pa@lungsurgeon.co.uk.
How quickly can I be seen?
Private consultations are typically available within two to three days. Contact Jo Mitchelson, Dr Okiror's PA, on 020 7952 2882 or pa@lungsurgeon.co.uk to arrange an appointment.

Book a Consultation

Appointments within 2–3 days. Surgery at London Bridge Hospital and The Lister Hospital Chelsea. Self-referrals welcome.

Book a Consultation → GP Referral Information

Jo Mitchelson, Private PA  · 020 7952 2882 · pa@lungsurgeon.co.uk

St Thomas' Hospital #1 UK · Guy's Hospital #2 UK · London Bridge Hospital #10 UK · Newsweek World’s Best Hospitals 2026

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